The St. Regis San Francisco is a striking landmark in the South of Market (SoMa) district, famously occupying the lower floors of the St. Regis Museum Tower. Opened in 2005 and designed by the renowned architectural firm Skidmore, Owings & Merrill, the building held the impressive title of the tallest concrete structure west of the Mississippi River at the time of its completion. Its design represents a sophisticated blend of neomodern architecture and high-end luxury.
What sets this hotel apart is its deep integration with the city’s artistic culture. The Museum of the African Diaspora is housed within the first three floors of the same tower, and the hotel sits directly adjacent to the San Francisco Museum of Modern Art (SFMOMA). The interior spaces are treated like a curated gallery, featuring a rotating collection of contemporary art pieces that guests can enjoy while moving through the lobby and halls.
The guest experience is defined by the brand’s legendary butler service, which provides personalized attention to every traveler. The rooms themselves are designed with a sleek, minimalist aesthetic, utilizing rich textures like leather and wood to offer a warm, high-contrast look that frames the sweeping views of the downtown skyline through floor-to-ceiling windows.
Its location is a dream for culture enthusiasts. Beyond the immediate neighbors of SFMOMA and the Yerba Buena Center for the Arts, guests are just a short walk from the bustling Union Square shopping district and the serene Yerba Buena Gardens, providing a perfect balance of city excitement and quiet relaxation.
Expert reviews
“Full-blown high-tech luxury is yours at this über-chic 40-story SoMa tower. Strategically near the Museum of Modern Art and Yerba Buena Gardens, this shrine to urban luxury welcomes guests with a 16-foot-long gas fireplace and streamlined lobby bar that’s frequented by city socialites.”
Featured as Frommer’s Exceptional Choice in San Francisco.
“Across from Yerba Buena and the MOMA, favored by celebrities such as Lady Gaga and Al Gore, St. Regis San Francisco is at once luxurious and modern.”
Featured as Fodor’s Choice in San Francisco.
“Since opening in 2005, The St. Regis San Francisco has been refining the concept of luxury, retaining the detail-oriented service focus and continuing its legacy of timeless elegance.”
What guests liked
- Friendly staff
- Clean rooms
- Great location
- Comfortable beds
Location
Recent guest reviews
13 March 2026
Fabulous
19 February 2026
Exceptional
8 December 2025
Fabulous
10 November 2025
Exceptional
8 November 2025
Fabulous
30 October 2025
Exceptional
30 August 2025
Very good
29 August 2025
Exceptional
21 August 2025
Fabulous
19 July 2025
Fabulous
16 July 2025
Exceptional
9 July 2025
Exceptional
10 June 2025
Fabulous
10 June 2025
Exceptional
27 May 2025
Fabulous
12 April 2025
Exceptional
27 March 2025
Exceptional
24 February 2025
Fabulous
2 January 2025
Exceptional
13 December 2024
Exceptional
7 August 2024
Exceptional
23 July 2024
Fabulous
15 April 2024
Exceptional
10 March 2024
Exceptional
15 February 2024
Fabulous
9 February 2024
Exceptional
14 January 2024
Fabulous
8 January 2024
Exceptional
3 January 2024
Exceptional
27 December 2023
Exceptional
12 December 2023
Very good
25 November 2023
Beautiful hotel. Good location.
23 November 2023
Exceptional
24 September 2023
Fabulous
10 August 2023
Exceptional
3 August 2023
Exceptional
2 August 2023
Exceptional
15 July 2023
Exceptional
26 June 2023
Fabulous
Hotel facilities
Food & Drink
- - Restaurant
- - Bar
- - Breakfast in the room
- - Special diet menus (on request)
- - Kids' meals
- - Wine/champagne (additional charge)
General
- - Room service
- - Non-smoking rooms
- - Facilities for disabled guests
- - Lift
- - Safety deposit box
- - Heating
- - Allergy-free room
- - Non-smoking throughout
- - Air conditioning
- - Shared lounge/TV area
- - Paid WiFi
- - Pet bowls
Business facilities
- - Meeting/banquet facilities (additional charge)
- - Business centre (additional charge)
Reception services
- - 24-hour front desk
- - Luggage storage
- - ATM/cash machine on site
- - Concierge service
Activities
- - Fitness centre
- - Indoor pool
- - Indoor pool (all year)
- - Fitness
Outdoors
- - Terrace
- - Outdoor furniture
Entertainment & family services
- - Babysitting/child services (additional charge)
Cleaning services
- - Dry cleaning (additional charge)
- - Daily housekeeping
Parking
- - Electric vehicle charging station
Accessibility
- - Wheelchair accessible
- - Toilet with grab rails
- - Raised toilet
- - Lower bathroom sink
- - Visual aids: Braille
Pool and wellness
- - Swimming pool
- - Swimming pool
Miscellaneous
- - 24-hour security
- - Key card access
- - Security alarm
- - Smoke alarms
- - CCTV in common areas
- - CCTV outside property
- - Fire extinguishers

More photos
17 April 2026
Pleasant